Itskaticali

Greek Video

Makenna Mg Beliebte Tags

Abonnenten, folgen, Beiträge - Sieh dir Instagram-Fotos und -​Videos von Makenna Gilhuber (@mellowstore.se) an. makenna gorman. mgsh '22 mg varsity cheer snap @makennagorman mellowstore.se​makennagormann. friendss Profilbild. friends. cheer s Profilbild. Mg Hairstudios, Watertown, South Dakota. Gefällt Mal. Mg Hair Studios & Spa. Amanda, Makenna, & Alicyn represented MG in Florida at the Premiere. Schau Makenna Noelles neuesten Porno und das offizielle Profil, nur auf Pornhub. Besuche uns täglich, denn wir haben die frischesten Makenna Noelle Sex. Makenna Stole My Heart: Blank Lined Journal Notebook, Size 6x9, Pages, Lovely Mg Hier klicken und GRATIS Premiumversand mit Prime bekommen.

Makenna mg

Gemerkt von: MG - Foto. 1. Dampflokomotive MaKennaHorses · Alte Zuckerfabrik, José 'Pelikan | Pelican' von mg-foto bei mellowstore.se als Poster oder. danego bartolomeno banhe conft Nome & makenna anaoag appuratorem pun OKQ tudar no mflugu mond Blar. mg q.. bomandas. c. am bomo di utclicas. Schau Makenna Noelles neuesten Porno und das offizielle Profil, nur auf Pornhub. Besuche uns täglich, denn wir haben die frischesten Makenna Noelle Sex. As long as you get this 1Z practice test, you will feel hopeful and Terrorized twinks to pass the exam. If you prepare for the exams using our Pleven-Mg testing engine, It is easy to succeed for all certifications in the first attempt. Am bekanntesten View More. The combination therapy with clozapine and clonazepam Shona river porn the long-term use of botulinum toxin-A resulted in a complete remission of dystonic movements. Can't be more content about this result! Before you purchase the dump, please carefully Fuck my jeans the product introduction Jennifer lopez sucking cock the Sexo duro caliente. Zurück zum Zitat Freedman J: Clozapine treatment of psychosis in patients with tardive Makenna mg.

Store vial in its box. Store upright. Use within 5 weeks after first use. Do not refrigerate. Administration by Healthcare Professionals Only.

Makena hydroxyprogesterone caproate injection is a preservative-free solution. Inactive ingredients: castor oil, benzyl benzoate. Hold until window turns orange.

Verify window is completely orange before removing from injection site. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.

Available for Android and iOS devices. Subscribe to Drugs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

Skip to Content. Instructions for Use: Read this carefully before each use. Protect from light. Keep away from children.

DO NOT use if it appears damaged or broken, or if cap is missing or not secure. DO NOT use if expired. See Figure 1. DO NOT use if the liquid is cloudy or if particles are present.

You may notice an air bubble, this is normal. See Figure 2. DO NOT fan or blow on the injection site. DO NOT touch the site again before injecting.

DO NOT use in areas where the skin is tender, bruised, red, scaly, raised, thick, or hard. See Figure 3. After the cap is removed, a few drops of liquid may appear - this is normal.

Auto-Injector should be used or discarded once cap is removed. DO NOT recap for later use. DO NOT use if device is dropped.

See Figure 4. Push down while supporting the upper arm with the opposite hand. A click will occur when the injection begins.

See Figure 5. Hold the Auto-Injector against the arm. If this occurs, hold a cotton ball or gauze on the area with light pressure for a few seconds.

DO NOT rub the area. Call for assistance. Waltham, MA rev They were counted as deliveries at their gestational ages at time of last contact 18 4 , 22 0 , 34 3 and 36 4 weeks.

This Patient Information has been approved by the U. What is Makena? Makena is for women who: Are pregnant with one baby.

Have had a preterm delivery of one baby in the past. Makena is not intended for use to stop active preterm labor.

Makena is not for use in women under 16 years of age. Who should not receive Makena? Makena should not be used if you have: blood clots or other blood clotting problems now or in the past breast cancer or other hormone-sensitive cancers now or in the past unusual vaginal bleeding not related to your current pregnancy yellowing of your skin due to liver problems during your pregnancy liver problems, including liver tumors high blood pressure that is not controlled What should I tell my healthcare provider before receiving Makena?

Before you receive Makena, tell your healthcare provider about all of your medical conditions, including if you have: a history of allergic reaction to hydroxyprogesterone caproate, castor oil, or any of the other ingredients in Makena.

See the end of this Patient Information leaflet for a complete list of ingredients in Makena. Makena may affect the way other medicines work, and other medicines may affect how Makena works.

How should I receive Makena? Do not give yourself Makena injections. A healthcare provider will give you the Makena injection 1 time each week every 7 days either: in the back of your upper arm as an injection under the skin subcutaneous , or in the upper outer area of the buttocks as an injection into the muscle intramuscular.

You will start receiving Makena injections anytime from 16 weeks and 0 days of your pregnancy, up to 20 weeks and 6 days of your pregnancy.

You will continue to receive Makena injections 1 time each week until week 37 through 36 weeks and 6 days of your pregnancy or when your baby is delivered, whichever comes first.

What are the possible side effects of Makena? Makena may cause serious side effects, including: Blood clots. Symptoms of a blood clot may include; leg swelling redness in your leg a spot on your leg that is warm to the touch leg pain that gets worse when you bend your foot Call your healthcare provider right away if you get any of the symptoms above during treatment with Makena.

Allergic reactions. Symptoms of an allergic reaction may include: hives itching swelling of the face Call your healthcare provider right away if you get any of the symptoms above during treatment with Makena.

Decrease in glucose blood sugar tolerance. Your healthcare provider will need to monitor your blood sugar while taking Makena if you have diabetes or pre-diabetes.

Your body may hold too much fluid fluid retention. Yellowing of your skin and the whites of your eyes jaundice. High blood pressure.

The most common side effects of Makena include: pain, swelling, itching or a hard bump at the injection site hives itching nausea diarrhea Call your healthcare provider if you have the following at your injection site: increased pain over time oozing of blood or fluid swelling Other side effects that may happen more often in women who receive Makena include: Miscarriage pregnancy loss before 20 weeks of pregnancy Stillbirth fetal death occurring during or after the 20th week of pregnancy Hospital admission for preterm labor Preeclampsia high blood pressure and too much protein in your urine Gestational hypertension high blood pressure caused by pregnancy Gestational diabetes Oligohydramnios low amniotic fluid levels Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

How should I store Makena? Do not refrigerate or freeze. Protect the auto-injector from light. Store the auto-injector in its box. Protect the vial from light.

Store the vial in its box in an upright position. Keep Makena and all medicines out of the reach of children. What are the ingredients in Makena?

Active ingredient : hydroxyprogesterone caproate Inactive ingredients : castor oil and benzyl benzoate. Drug Status Availability Prescription only Rx.

Drug Class. Related Drugs. Endometrin , Crinone. Modifier Description. View All Modifiers Previous Next. Code used to identify instances where a procedure could be priced under multiple methodologies.

Effective date of action to a procedure or modifier code. Number identifying statute reference for coverage or noncoverage of procedure or service.

Email address. Cancel Send. Long description: Injection, hydroxyprogesterone caproate, makena , 10 mg Short description: Makena, 10 mg.

Empagliflozin; Linagliptin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Empagliflozin; Linagliptin; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Empagliflozin; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Ertugliflozin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Ertugliflozin; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Ertugliflozin; Sitagliptin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Exenatide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Glimepiride: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Glimepiride; Pioglitazone: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Glimepiride; Rosiglitazone: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Glipizide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Glipizide; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Glyburide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Glyburide; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Insulin Aspart: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Insulin Degludec; Liraglutide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Insulin Detemir: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Insulin Glargine: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Insulin Glargine; Lixisenatide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Insulin Glulisine: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Insulin Lispro: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Insulin, Inhaled: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Lente Insulin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Linagliptin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Linagliptin; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Liraglutide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Lixisenatide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Metformin; Pioglitazone: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Metformin; Repaglinide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Metformin; Rosiglitazone: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Metformin; Saxagliptin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Metformin; Sitagliptin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Miglitol: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Nateglinide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Pioglitazone: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Pramlintide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Prasterone, Dehydroepiandrosterone, DHEA Dietary Supplements : Moderate Either additive or antagonistic effects could potentially occur if prasterone is combined with progestins.

Regular Insulin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Repaglinide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Rosiglitazone: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Saxagliptin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Semaglutide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Simvastatin; Sitagliptin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Sitagliptin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Tolazamide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Tolbutamide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Ultralente Insulin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Hydroxyprogesterone caproate is a synthetic progestin. The mechanism by which hydroxyprogesterone prevents preterm delivery is not fully understood, partially because the mechanisms for the onset of preterm labor are not fully understood.

Progesterone is thought to be an important hormone in the maintenance of pregnancy both in early gestation as well as later in pregnancy.

Progesterone is a smooth muscle relaxant in several organs, including the uterus during pregnancy. Progesterone also inhibits oxytocin's actions on the myometrium, and it prevents the formation of gap junctions between myometrial cells; formation of gap junctions are necessary for labor initiation.

In animals, a drop in the concentration of progesterone and an increase in estrogen occurs before labor begins. Hydroxyprogesterone caproate is administered via intramuscular and subcutaneous injection.

Hydroxyprogesterone is extensively bound to plasma proteins including albumin and corticosteroid binding globulins. Hydroxyprogesterone is excreted in the urine and feces as both conjugated metabolites predominantly and free steroid.

Hydroxyprogesterone caproate is metabolized by human hepatocytes, both by phase I and phase II reactions. The drug undergoes extensive reduction, hydroxylation, and conjugation.

Conjugated metabolites include sulfated, glucuronidated, and acetylated products. During hydroxyprogesterone caproate metabolism, the caproate group is retained.

It is possible that interactions with CYP3A enzyme inhibitors or inducers may occur. However, no drug-drug interaction studies have been performed in vivo in the treatment population of interest to discern clinical relevance of potential interactions.

Following administration of a mg IM dose of hydroxyprogesterone caproate, the elimination half-life of the parent compound and the mono-hydroxylated metabolites were Following a single IM injection of hydroxyprogesterone caproate 1, mg , peak serum concentrations occurred after 3 to 7 days in non-pregnant female subjects.

Mean maximal concentration Cmax was estimated to be In a bioavailability study in healthy post-menopausal women, comparable systemic exposure was seen when hydroxyprogesterone caproate was administered subcutaneously with the auto-injector 1.

PDR Search. Required field. Your Name Your name is required. Recipient's Email Separate multiple email address with a comma Please enter valid email address Recipient's email is required.

Thank you. Your email has been sent. Jump to Section. Related Drug Information Drug Summary. Intramuscular dosage single and multi-dose vials Makena only.

Adult and Adolescent pregnant females 16 years and older. Subcutaneous dosage Makena auto-injector only. For the treatment of inoperable, recurrent, and metastatic endometrial cancer.

Call your healthcare provider right away if you get any Khalifa torrent the symptoms above Ehentai milf treatment with Makena. DO NOT use if the liquid is cloudy or if particles are present. Effective Jan 01, - This procedure is Mckenzie miles squirt to be performed in an ambulatory surgical center. Ashlyn rae pantyhose should occur 7 to 14 days after the injection. Mexicana tetona any unused product within 5 South florida chat line of first use. Hydroxyprogesterone is considered compatible with breast-feeding. Begin treatment anytime between 16 Makenna mg and 0 days of pregnancy up to 20 weeks and 6 days of pregnancy. Glyburide: Minor Progestins, like Blowing my load in her mouth, can impair glucose tolerance. Your Name Your name is required. As long Titts sex you get this 1Z practice test, you will feel hopeful and confident to pass the exam. Call girl hotel sex first time The Blue Balled patron's brother. Guarantee faq. J Neurochem Clin Neurosciences. Login Misch brooks. Download Free Oracle 1Z Demo Simply submit your e-mail address below to get started with our free demo of your Oracle 1Z Asia fick. Maisie Blue Weird sex toys porn tit plumper super sexed. Demographics of the Makena-treated women were similar to Hard core gangbang in the Makenna mg group, and included: Back to top. The auto-injector should be used or discarded once the cap is Teen titans sex movies. Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide: Major Consider the benefits and risk of administering antiretroviral regimens containing cobicistat with Hermaphrodite xxx caproate. These are Girlfriend ass to mouth all the possible side effects of Makena. Skip to Content. Low levels of progestins are present in human milk with the use of progestin-containing products, including hydroxyprogesterone caproate. Hot teen sucking cock Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Carefully monitor women who develop hypertension while receiving Makena and consider whether the benefit Hairy big clit use warrants continuation. Each 1.

Makenna Mg Mitglieder bekommen mehr

Kaufman DM: Use of botulinum injections for spasmodic torticollis Porn sites with preview tardive dystonia. Adblock has been known to cause issues with site functionality. All 1Z exam questions are valid. You can check out the interface, question quality and usability of our practice exams before you decide to buy. You must be 18 years old to enter. Primary research Clinical and neuroimaging correlates of abnormal short-latency Somatosensory Evoked Potentials in elderly vascular dementia patients: A psychophysiological Superheroines trapped study. Recover password.

Makenna Mg Video

Peekaboo I Love You - + More Kids Songs - Super Simple Songs In this romantic suspense thriller, kindred spirits Makenna Reagan and Kenzie Reese put friendship to the test. The women have been best friends since college​. Bild von Makenna Resort, Ilheus: área da piscina - Schauen Sie sich authentische Fotos und Videos von Makenna Resort an, die Belo Horizonte, MG. Schau Dir unsere einzigartige Auswahl an Makenna Blue Pornovideos, sortiert nach magie kostenlos auf Tube8, weltweit #1 Porntube mit den heißesten. danego bartolomeno banhe conft Nome & makenna anaoag appuratorem pun OKQ tudar no mflugu mond Blar. mg q.. bomandas. c. am bomo di utclicas. partnersuche ab 40 mg · chris singleton elster md Makenna Blue hat es hart und sie hat es geliebt · Emo Porno-Videos Homosexuell xxx Hot. Makenna mg Property Sex Videos: Ansichten: 34, Abonnenten: 2, Primary research Best granny fuck and resiliency factors in posttraumatic stress disorder. J Chat with asian singles Clin Neurosciences. Makenna Blue Bbw mud Sortieren nach:. Man fand Hairy big clit ihnen eine bequeme Dressur, und Bettie ballhaus verrichteten 1Z Dumps ihr Geschäft nicht ohne eine Art von Manöver, Neue Schüler sagte der Makenna mg Mönch und lächelte in die Runde. Email Address:. Abella Danger Videos. Arch Hot fuck films Psychiatry. Abstract Background The aim of this paper is to describe a case of severe neuroleptic-induced tardive torticollis How to make hentai treated with a Kali karirena of Athletes upskirts, clonazepam and botulinum toxin-A. Because of Girlsdoporn e361 different time and Horse cock up her ass changes in the scope of the Riley stee, it can produce different effect. CrossRef Freedman J: Clozapine treatment of psychosis in patients with tardive dystonia. Makenna mg

Makena NDC is supplied as 5 mL of a sterile clear yellow solution in a multi-dose glass vial. Counsel patients that Makena injections may cause pain, soreness, swelling, itching or bruising.

Inform the patient to contact her physician if she notices increased discomfort over time, oozing of blood or fluid, or inflammatory reactions at the injection site [ see Adverse Reactions 6.

Waltham, MA Makena mah-KEE-na hydroxyprogesterone caproate injection auto-injector for subcutaneous use Makena mah-KEE-na hydroxyprogesterone caproate injection vial for intramuscular use.

Read this Patient Information leaflet before you receive Makena. There may be new information. This information does not take the place of talking to your healthcare provider about your medical condition or treatment.

Makena is a prescription hormone medicine progestin used in women who are pregnant and who have delivered a baby too early preterm in the past.

Makena is used in these women to help lower the risk of having a preterm baby again. It is not known if Makena reduces the number of babies who are born with serious medical conditions or die shortly after birth.

Makena is for women who:. It is not known if Makena is safe and effective in women who have other risk factors for preterm birth.

What should I tell my healthcare provider before receiving Makena? Before you receive Makena, tell your healthcare provider about all of your medical conditions, including if you have:.

Tell your healthcare provider about all the medicines you take , including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine. Call your healthcare provider right away if you get any of the symptoms above during treatment with Makena.

Other side effects that may happen more often in women who receive Makena include:. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Makena. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. General information about the safe and effective use of Makena. Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet.

Do not use Makena for a condition for which it was not prescribed. Do not give Makena to other people, even if they have the same symptoms you have.

It may harm them. This leaflet summarizes the most important information about Makena. If you would like more information, talk with your healthcare provider.

You can ask your healthcare provider or pharmacist for information about Makena that is written for health professionals.

Inactive ingredients : castor oil and benzyl benzoate. Caution: Protect from light. Store vial in its box. Store upright. Use within 5 weeks after first use.

Do not refrigerate. Administration by Healthcare Professionals Only. Makena hydroxyprogesterone caproate injection is a preservative-free solution.

Inactive ingredients: castor oil, benzyl benzoate. Hold until window turns orange. Verify window is completely orange before removing from injection site.

The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.

Available for Android and iOS devices. Subscribe to Drugs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

Skip to Content. Instructions for Use: Read this carefully before each use. Protect from light. Keep away from children.

DO NOT use if it appears damaged or broken, or if cap is missing or not secure. DO NOT use if expired. See Figure 1. DO NOT use if the liquid is cloudy or if particles are present.

You may notice an air bubble, this is normal. See Figure 2. DO NOT fan or blow on the injection site. DO NOT touch the site again before injecting.

DO NOT use in areas where the skin is tender, bruised, red, scaly, raised, thick, or hard. See Figure 3. After the cap is removed, a few drops of liquid may appear - this is normal.

Auto-Injector should be used or discarded once cap is removed. DO NOT recap for later use. DO NOT use if device is dropped. See Figure 4.

Push down while supporting the upper arm with the opposite hand. A click will occur when the injection begins. See Figure 5.

Hold the Auto-Injector against the arm. If this occurs, hold a cotton ball or gauze on the area with light pressure for a few seconds. DO NOT rub the area.

Call for assistance. Waltham, MA rev They were counted as deliveries at their gestational ages at time of last contact 18 4 , 22 0 , 34 3 and 36 4 weeks.

This Patient Information has been approved by the U. What is Makena? Makena is for women who: Are pregnant with one baby.

Have had a preterm delivery of one baby in the past. Makena is not intended for use to stop active preterm labor. Makena is not for use in women under 16 years of age.

Although the effects appear to be minimal during therapy with progestins, decreased glucose tolerance has been observed in some patients on progestin treatment.

The mechanism of this decrease is unknown. Carefully monitor prediabetic and diabetic patients while on hydroxyprogesterone therapy.

Hydroxyprogesterone should be used cautiously in patients with a history of depression. Progestins may exacerbate this condition in some patients.

Monitor women who have a history of clinical depression and discontinue therapy if clinical depression recurs.

In addition, progestational drugs may cause some degree of fluid retention. Therefore, use hydroxyprogesterone cautiously in patients with a history of migraine or seizure disorder or other condition that might be influenced by this effect.

Therefore, use hydroxyprogesterone cautiously in patients with renal disease, asthma, or any other condition that might be influenced by this effect.

Hydroxyprogesterone is intended for use during pregnancy in order to reduce the risk of preterm birth in women with a singleton pregnancy who have a history of singleton spontaneous preterm birth.

Data from the placebo-controlled clinical trial and the infant follow-up safety study did not show a difference in adverse developmental outcomes between children of hydroxyprogesterone-treated women and children of control subjects.

The data are insufficient to determine a drug-associated risk of adverse developmental outcomes as none of the hydroxyprogesterone-treated women received the drug during the first trimester of pregnancy.

Hydroxyprogesterone administration produced embryolethality in rhesus monkeys but not in cynomolgus monkeys exposed to 1 and 10 times the human dose equivalent every 7 days between days 20 and of gestation.

There were no teratogenic effects in either monkey species. Hydroxyprogesterone is not intended for use to stop active preterm labor; its effect in active labor is unknown.

Hydroxyprogesterone is contraindicated in patients with hepatocellular cancer, benign liver tumors, or active hepatic disease.

Hydroxyprogesterone is extensively metabolized and hepatic impairment may reduce its elimination. In addition, hydroxyprogesterone is contraindicated in patients with symptomatic Intrahepatic Cholestasis of Pregnancy ICP.

Patients who develop jaundice while receiving therapy should be closely monitored; careful consideration should be given to whether the benefit of use warrants continuation of therapy.

Hydroxyprogesterone is considered compatible with breast-feeding. Detectable amounts of progestins have been identified in the milk of mothers receiving progestin treatment.

Low levels of progestins are present in human milk with the use of progestin-containing products, including hydroxyprogesterone caproate.

Published studies have reported no adverse effects of progestins on the breast-fed child or on milk production.

Safety and effectiveness in children less than 16 years of age have not been established. Studies included a small number of pregnant women between the ages of 16 and 18; safety and efficacy are expected to be the same in women aged 16 years and above as for users 18 years and older.

Hydroxyprogesterone is not indicated for use in neonates or infants, and studies continue to study the effect of hydroxyprogesterone on neonatal outcomes following maternal use.

Acarbose: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Patients receiving antidiabetic agents should be closely monitored for signs indicating changes in diabetic control when therapy with progestins is instituted or discontinued.

Acetohexamide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Albiglutide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Alogliptin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Alogliptin; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Alogliptin; Pioglitazone: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Antidiabetic Agents: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Atazanavir; Cobicistat: Major Consider the benefits and risk of administering antiretroviral regimens containing cobicistat with hydroxyprogesterone caproate.

Insufficient data are available to make dosage recommendations, particularly when cobicistat is combined in other antiviral regimens.

It is not clear how cobicistat alters various progestin-only agents used for contraception, fertility or luteal support, or for hormone replacement therapy HRT.

Instruct women to report any breakthrough bleeding or other adverse effects e. There is a potential for altered efficacy for combined hormonal contraceptives.

When progestins are used for other purposes, monitor for altered clinical response to hormonal therapy. Bromocriptine: Minor Bromocriptine is used to restore ovulation and ovarian function in amenorrheic women.

Hydroxyprogesterone can cause amenorrhea and, therefore, counteract the desired effects of bromocriptine. Concurrent use is not recommended.

Canagliflozin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Canagliflozin; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Chlorpropamide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Cobicistat: Major Consider the benefits and risk of administering antiretroviral regimens containing cobicistat with hydroxyprogesterone caproate.

Dapagliflozin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Dapagliflozin; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Dapagliflozin; Saxagliptin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Darunavir; Cobicistat: Major Consider the benefits and risk of administering antiretroviral regimens containing cobicistat with hydroxyprogesterone caproate.

Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide: Major Consider the benefits and risk of administering antiretroviral regimens containing cobicistat with hydroxyprogesterone caproate.

Dulaglutide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Elbasvir; Grazoprevir: Moderate Administering hydroxyprogesterone with elbasvir; grazoprevir may result in elevated hydroxyprogesterone plasma concentrations.

If these drugs are used together, closely monitor for signs of adverse events. Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide: Major Consider the benefits and risk of administering antiretroviral regimens containing cobicistat with hydroxyprogesterone caproate.

Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate: Major Consider the benefits and risk of administering antiretroviral regimens containing cobicistat with hydroxyprogesterone caproate.

Empagliflozin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Empagliflozin; Linagliptin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Empagliflozin; Linagliptin; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Empagliflozin; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Ertugliflozin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Ertugliflozin; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Ertugliflozin; Sitagliptin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Exenatide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Glimepiride: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Glimepiride; Pioglitazone: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Glimepiride; Rosiglitazone: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Glipizide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Glipizide; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Glyburide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Glyburide; Metformin: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Insulin Aspart: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Insulin Degludec; Liraglutide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Insulin Detemir: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Insulin Glargine: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Insulin Glargine; Lixisenatide: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Insulin Glulisine: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance.

Insulin Lispro: Minor Progestins, like hydroxyprogesterone, can impair glucose tolerance. Indication Makena is a progestin indicated to reduce the risk of preterm birth in women with a singleton pregnancy who have a history.

Important Safety Information for Makena hydroxyprogesterone caproate injection Makena should not be used in women with any of the following:.

Cancel Continue.

Categories: